LACTULOSE

COMPOSITION

    Each sachet (15ml) of Lactulose solution contains:

    -  Lactulose.................................................................................................10g.

INDICATIONS

    -  Prophylaxis of hepatic encephalopathy.

    -  Chronic constipation.

DOSAGE AND ADMINISTRATION

    -  Prophylaxis of hepatic encephalopathy.

      * Adults: Initially 20 - 30g, 3 times daily. Subsequently adjust the dose every 1 - 2 days as necessary to produce two or three soft stools eachday.

      * Infants: 2 - 6g daily, in divided doses.

      * Older children and adolescents: 30 - 60g daily, in divided doses. Subsequently adjust the dose every 1 - 2 days as necessary to produce two or

 three soft stools each day. If initial dose causes diarrhea, reduce dose immediately, if diarrhea persists, discontinue.

    -  Constipation: Initially, lactulose may be given twice daily. In due course, the dose should be adjusted to the need of the individual, but the following serves as guide:

      * Adults: 10g twice daily, increase to 40g daily if necessary. Maintenance doses are 7 to 10g daily.

      * Children 5 - 10 years: 6g twice daily.

      * Children under 5 years: 3g twice daily.

      * Chilren under 1 years: 2g twice daily.   

CONTRAINDICATIONS

    -  Hypersensitivity to any of the components of  drug.

    -  Patients with galactosemia and requiring a low lactose diet.

PRECAUTIONS

       Patients with diabetes because of small amounts of free lactose and galactose in some dosage forms.